Introduction to quantitative genetics falconer downloadFalconer Author , Trudy F. Mackay Author. Introduction to Quantitative Genetics [Douglas S. Falconer and Trudy F. Mackay] on exaceqomopon. Printed in Asia. In his career he made many important contributions to quantitative genetics and to the genetics of.
Introduction to Quantitative Genetics (4th Edition)
Quantitative genetics theory for non-inbred populations in linkage disequilibrium. Although linkage disequilibrium, epistasis and inbreeding are common phenomena in genetic systems that control quantitative traits, theory development and analysis are very complex, especially when they are considered together. The objective of this study is to offer additional quantitative genetics theory to define and analyze, in relation to non-inbred cross pollinating populations, components of genotypic variance, heritabilities and predicted gains, assuming linkage disequilibrium and absence of epistasis. The genotypic variance and its components, additive and due to dominance genetic variances, are invariant over the generations only in regard to completely linked genes and to those in equilibrium. When the population is structured in half-sib families, the additive variance in the parents' generation and the genotypic variance in the population can be estimated. When the population is structured in full-sib families, none of the components of genotypic variance can be estimated.
Day 1: (Monday, 4 August )
The presence of heterosis has been observed in many species at both phenotypic and gene levels. Strangely, the genetic basis of heterosis was and still is largely unknown. In this study, we extended and simplified some formulas that we reported previously. The foundation of our model was based on partitioning the F 1 phenotypic variance of the cross between two pure lines into additive, dominance and epistasis components, which lead to the estimation of effective factors, crossheritability in the broad and narrow sense and heterotic power. In the model, we assume that all polygenes controlling a quantitative trait have an equal genetic effect and are independent of each other. By extension of the heritability to a cross population, new features appear. Lastly, an example of employing the proposed method in analyzing the crossing data from Drosophila melanogaster is given to illustrate its application.