Fundamentals of Protein Structure and Function : Engelbert Buxbaum :This book serves as an introduction to protein structure and function. Starting with their makeup from simple building blocks, called amino acids, the 3-dimensional structure of proteins is explained. Enzymology and modern concepts of enzyme kinetics are then introduced, taking into account the physiological, pharmacological, and medical significance of this often neglected topic. The book emphasises the link between protein structure, physiological function, and medical significance. This book can be used for graduate and advanced undergraduate classes covering protein structure and function and as an introductory text for researchers in protein biochemistry, molecular and cell biology, chemistry, biophysics, biomedicine, and related courses. He has been working on the biochemistry of membrane transport proteins for nearly thirty years and has taught courses in biochemistry and biomedicine at several universities. Skip to main content Skip to table of contents.
Fundamentals of Protein Structure and Function
NCBI Bookshelf. Proteins are the most versatile macromolecules in living systems and serve crucial functions in essentially all biological processes. They function as catalysts, they transport and store other molecules such as oxygen, they provide mechanical support and immune protection, they generate movement, they transmit nerve impulses, and they control growth and differentiation. Indeed, much of this text will focus on understanding what proteins do and how they perform these functions. Proteins are linear polymers built of monomer units called amino acids. The construction of a vast array of macromolecules from a limited number of monomer building blocks is a recurring theme in biochemistry.
Table of contents
Use the link below to share a full-text version of this article with your friends and colleagues. Learn more. To understand the relationship between a protein's structure and function fully, knowledge of that protein's evolutionary history and its interactions is essential. Therefore, we describe the mechanisms by which proteins have evolved. We also describe how molecular recognition drives protein interactions and the types of interaction that take place. Encyclopedia of Genetics, Genomics, Proteomics and Bioinformatics. The full text of this article hosted at iucr.
This book serves as an introduction to the fundamentals of protein structure and function. Starting with their make up from simple building blocks called amino acids, the 3-dimensional structure of proteins is explained. This is followed by an introduction into enzymology and modern concepts of enzyme kinetics, taking into account the physiological and medical significance of this often neglected topic. Also covered in the text are enzymes, biocatalysts, enzyme kinetics, hemoglobin, myoglobin, prion proteins, immunoproteins, motor proteins and movement, cell-cell interactions, molecular chaperones and chaperonins, transport of proteins into mitochondria, transport of proteins between cell compartments, transport of solutes across membranes, analytic techniques, protein-ligand interactions, protein purification, and protein structure, size and shape, emphasizing the link between protein structure, physiological function and medical significance. This book is an introductory text for researchers in protein biochemistry, molecular biology, cell biology, chemistry, biophysics and biomedical research.